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HeartCited

Vitamin K2 Arterial Stiffness

B

Rotterdam Heart Study: 57% lower CV mortality with highest K2 intake. KNAPEN RCT: MK-7 (180 mcg/day, 3 years) significantly improved arterial stiffness in postmenopausal women.

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B

結論

Rotterdam Heart Study: 57% lower CV mortality with highest K2 intake. KNAPEN RCT: MK-7 (180 mcg/day, 3 years) significantly improved arterial stiffness in postmenopausal women.

Key Statistics

5

研究数

1200

参加者数

Positive

B

グレード

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:
90-120 mcg/day (MK-7 preferred)
cardiovascularsupport:
180-360 mcg/day MK-7

上限量: Not established (no known toxicity for K2 at supplemental doses)

推奨摂取タイミング: With meals containing fat; can combine with vitamin D supplement

Safety & Side Effects

報告されている副作用

  • Generally very well-tolerated
  • Does not affect blood clotting (INR) at supplemental doses, unlike K1

既知の相互作用

  • Warfarin (patients on warfarin should consult physician before K2 supplementation)
  • Vitamin D (synergistic — D increases MGP production, K2 activates it)

耐容上限摂取量: Not established (no known toxicity for K2 at supplemental doses)

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Vitamin K2 help with Arterial Stiffness?
Based on 5 studies with 1,200 participants, there is moderate evidence from clinical studies that Vitamin K2 may support Arterial Stiffness management. Our evidence grade is B (Good Evidence).
How much Vitamin K2 should I take for Arterial Stiffness?
Studies have used various dosages. A commonly studied range is 90-120 mcg/day (MK-7 preferred). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin K2?
Reported side effects may include Generally very well-tolerated, Does not affect blood clotting (INR) at supplemental doses, unlike K1. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin K2 and Arterial Stiffness?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 1,200 total participants. The overall direction of effect is positive.

Related Evidence

に関する他の成分: Arterial Stiffness

FDAに関する免責事項: これらの記述は米国食品医薬品局(FDA)による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。