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Vitamin K2 per Arterial Stiffness

B

Rotterdam Heart Study: 57% lower CV mortality with highest K2 intake. KNAPEN RCT: MK-7 (180 mcg/day, 3 years) significantly improved arterial stiffness in postmenopausal women.

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In sintesi

            
            
Rotterdam Heart Study: 57% lower CV mortality with highest K2 intake. KNAPEN RCT: MK-7 (180 mcg/day, 3 years) significantly improved arterial stiffness in postmenopausal women.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
Studi

    

    

        
1200

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Grado

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
90-120 mcg/day (MK-7 preferred)

                    

                    
                    

                        
cardiovascularsupport:

                        
180-360 mcg/day MK-7

                    

                    
                

                
                

                    Limite massimo: Not established (no known toxicity for K2 at supplemental doses)
                

                
            

            

            

            
            

                Momento migliore per l'assunzione: With meals containing fat; can combine with vitamin D supplement
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Generally very well-tolerated
                        
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  • 
                            ⚠
                            Does not affect blood clotting (INR) at supplemental doses, unlike K1
                        
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Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Warfarin (patients on warfarin should consult physician before K2 supplementation)
                        
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  • 
                            ●
                            Vitamin D (synergistic — D increases MGP production, K2 activates it)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: Not established (no known toxicity for K2 at supplemental doses)
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Vitamin K2 help with Arterial Stiffness?
            
        
        

            Based on 5 studies with 1,200 participants, there is moderate evidence from clinical studies that Vitamin K2 may support Arterial Stiffness management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Vitamin K2 should I take for Arterial Stiffness?
            
        
        

            Studies have used various dosages. A commonly studied range is 90-120 mcg/day (MK-7 preferred). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Vitamin K2?
            
        
        

            Reported side effects may include Generally very well-tolerated, Does not affect blood clotting (INR) at supplemental doses, unlike K1. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Vitamin K2 and Arterial Stiffness?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 1,200 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Altri ingredienti per Arterial Stiffness

                    

                        
                        
                            NMN (Nicotinamide Mononucleotide)
                            C

                        
                        
                    

                

                

                
            

        

        

    


    
    












    

        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.