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Vitamin K2 untuk Arterial Stiffness

B

Rotterdam Heart Study: 57% lower CV mortality with highest K2 intake. KNAPEN RCT: MK-7 (180 mcg/day, 3 years) significantly improved arterial stiffness in postmenopausal women.

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B

Kesimpulan

Rotterdam Heart Study: 57% lower CV mortality with highest K2 intake. KNAPEN RCT: MK-7 (180 mcg/day, 3 years) significantly improved arterial stiffness in postmenopausal women.

Key Statistics

5

Studi

1200

Peserta

Positive

B

Peringkat

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
90-120 mcg/day (MK-7 preferred)
cardiovascularsupport:
180-360 mcg/day MK-7

Batas atas: Not established (no known toxicity for K2 at supplemental doses)

Waktu terbaik diminum: With meals containing fat; can combine with vitamin D supplement

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Generally very well-tolerated
  • Does not affect blood clotting (INR) at supplemental doses, unlike K1

Interaksi yang Diketahui

  • Warfarin (patients on warfarin should consult physician before K2 supplementation)
  • Vitamin D (synergistic — D increases MGP production, K2 activates it)

Asupan atas yang dapat ditoleransi: Not established (no known toxicity for K2 at supplemental doses)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Vitamin K2 help with Arterial Stiffness?
Based on 5 studies with 1,200 participants, there is moderate evidence from clinical studies that Vitamin K2 may support Arterial Stiffness management. Our evidence grade is B (Good Evidence).
How much Vitamin K2 should I take for Arterial Stiffness?
Studies have used various dosages. A commonly studied range is 90-120 mcg/day (MK-7 preferred). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin K2?
Reported side effects may include Generally very well-tolerated, Does not affect blood clotting (INR) at supplemental doses, unlike K1. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin K2 and Arterial Stiffness?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 1,200 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Arterial Stiffness

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.